What are Atypia and High-Risk Lesions?

Sometimes a diagnosis of a lump or a change in the breast is not straightforward in terms of interpretation of your laboratory results. The majority of patients will end up having a benign diagnosis (no cancer), such as fibroadenoma, cyst or fibrocystic change. Some patients will unfortunately have a breast cancer diagnosis and will need treatment.


However, there is an intermediate group of patients who may be diagnosed with so called atypia or high-risk lesions of the breast. This is not breast cancer but is not definitely benign either. Atypia and high-risk lesions can carry additional breast cancer risk for the future. This means that your breast may be at a higher risk of developing breast cancer in the future (breast at risk), compared to the general population.

What is the risk associated with Atypia and High-risk lesions?

The general population risk of developing breast cancer in a woman with a life span of 70 years old is about 12% or about one in eight women. Atypia and high-risk lesions can raise your risk up to 25% (i.e. about double the near-population risk).

What happens if I am diagnosed with a high-risk lesion?

If Mr Charalampoudis diagnoses one of those high-risk lesions in your breast, he will allocate you to annual clinical and mammographic surveillance for at least 5 years.

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